Immediately following her birth, her father posted the debut tweet and accompanying video "Welcome to the world. Ameera Reign."
Her parents began dating after her father appeared in her mother's music video for the single "That's Me Right There."
She has one aunt through her father and three uncles through her mother. She has three younger half siblings named Avayah, Zayne, and Aylah.
She is the child of a celebrity power couple much like Saint West.