His first name is Clarke, but he goes by his middle name, Isaac. He and his brothers founded their eponymous band in 1992.
He plays both the electric and acoustic guitar, as well as synths, bass, and piano. He and his brothers founded a beer brand called MMMhop.
He married Nicole Dufresne on September 30, 2006 and they had two sons and a daughter together.
The band performed a cover of "Never Been to Spain" with Conan O'Brien in 2010 during the latter's Prohibited Tour.