Nicknamed Locomotora, he was a former middleweight champion of the world, best known for his title defense in 1994.
As a child, he was in a bicycle accident so severe that doctors told him he'd never be able to box.
His 1994 comeback against John David Jackson, who appeared to have won the fight, is considered one of the greatest turnarounds in boxing history.
He married Belen Castro in 1998.
He and New York boxer Iran Barkley have been been WBA Middleweight champions.