Perhaps known best for her Cesar Award-nominated performance as Cecile in the 2005 film Il ne Faut Jurer de Rien!, Doutey also appeared in the 2003 movie La Fleur du Mal and in several episodes of the television series Clara Sheller.
Early in her career, she played the title role in the 2001 Danish movie Leila.
She appeared in the music video for singer Calogero's single "En Apesanteur."
She was born in Paris, France, to actors Arielle Semenoff and Alain Doutey. Her relationship with film actor Gilles Lellouche resulted in a daughter named Ava.
Doutey briefly appeared with Jean Dujardin in the 2011 movie Les Infideles; however, her scene was ultimately deleted from the film.