Writer and director of science fiction films such as Cube, Cypher, Nothing, and Splice.
He worked as a storyboard artist at the Nelvana Animation Studios.
His 1997 film Cube broke box office records for a Canadian film and won the award for Best Canadian First Feature at the Toronto International Film Festival.
His father was a photographer and his mother was a schoolteacher.
His 2009 science fiction horror film Splice featured Adrien Brody as a scientist.