Notable for his portrayal of Jason Roscoe on the popular British soap opera Hollyoaks, Browne-Sykes first appeared on the series on May 23, 2013. He has earned over 100,000 Twitter followers.
Before appearing on Hollyoaks, he guest starred in episodes of The Bill, Doctors, and Waking the Dead.
He played the role of Freddie in the 2013 film Beat Girl.
He was born and raised in England. Though they are not actually related, he and Charlie Wernham played twin brothers Jason and Robbie Roscoe on Hollyoaks.
His Hollyoaks mother was portrayed by Gillian Taylforth.