One of the first doctors to isolate insulin in order to control diabetes in animal trials.
He joined Dr. Frederick Banting's laboratory to assist him in research on insulin.
He got into Banting's lab with sheer luck, the flip of a coin actually. Had he lost the flip, history could have gone completely differently.
His son, Dr. Henry Best, was president of Laurentian University in Sudbury, Ontario.
He became a member of the National Inventors Hall of Fame along with GPS inventor Roger Easton.