Won the International Boxing Federation bantamweight title and defended it a record 16 times.
He turned professional in 1984 and was undefeated in his first 12 fights.
He was inducted into the International Boxing Hall of Fame on July 14, 2009.
His brother is fellow bantamweight champion Gaby Canizales.
He suffered a 12-round split decision loss to WBA champion Wilfredo Vazquez in 1995.