He was a DJ SW-1 on In Living Color, a show created by his older brother Keenan and featuring his other siblings.
He wrote for The Wayans Bros. TV series that lasted from 1995 until 1999.
He was born the second-youngest of ten siblings to parents Howell and Elvira Wayans. He grew up in the Fulton House projects in the Chelsea neighborhood of Manhattan. He has a son named Marlon and two daughters named Laila and Illia.
He starred in White Chicks and Little Man alongside his brother Marlon Wayans.