Youngest Wayans brother who first became known to audiences on the TV series In Living Color and The Wayans Bros. In 2017, he created and starred in his own show called Marlon. His film roles include White Chicks, Scary Movie and Scary Movie 2.
He began his film career by appearing as a pedestrian in I'm Gonna Git You Sucka in 1988.
He grew up in the projects. His father was a hotel manager and his mother stayed home to take care of him and his siblings: Shawn, Keenen, Damon, and Kim. He married Angelica Zachary in 2005. He has a son named Shawn and a daughter named Amai.
Actor Damon Wayans, Jr. is his nephew.