She played roles in the 1987 film Promised Land and also appeared in A Stranger Among Us. Her starring role as Ellen Reed in Family Ties brought her a great deal of fame.
She had her acting debut in the TV movie For Lovers Only.
She earned a 2000 Primetime Emmy Award nomination for her guest role onLaw & Order: Special Victims Unit.
She got married to Michael J. Fox in 1988; the couple had four children: Aquinnah, Sam, Esme and Schuyler.
She co-starred in the 2009 TV movie, Natalee Holloway, with Catherine Dent .