Sang with his brothers, Charles and Cyril in the Neville Brothers.
He practiced and performed with his brothers from an early age.
His heritage is African American & Native American, and his music, which he preformed with his brothers, is Cajun and Creole influenced.
He got married to Joel Roux-Neville on January 10, 1959, and then later to Sarah A. Friedman on November 13, 2010.
His first major hit single, Tell It Like It Is, was later remade and featured Nancy Wilson.