Famous for hosting the South African television entertainment programs Live Amp (on the SABC 1 channel) and Top Billing (on SABC 3), she is also notable as the host of the radio show The Front Row. Also a model and fashion icon, she won an SA Style Award and was photographed for the covers of Grazia, Elle, and Cosmopolitan South Africa.
She joined Twitter in 2010 and, by 2015, had over one million followers.
She created a fashion line called Just B and a handbag collection called Baby Star.
Nicknamed "Queen B," Matheba spent her youth in Mahikeng, South Africa.
She and American screen star Halle Berry both became spokesmodels for the Revlon cosmetics brand.