Best known for her Emmy-nominated portrayal of Dr. Faye Miller on the hit AMC series Mad Men, she is also notable for her roles as Karen Wheeler in Netflix's Stranger Things and Kelli on The Sopranos. Her film credits include Hulk, Next Stop Wonderland, Happy Accidents and Paper Towns.
After graduating from Columbia University with a bachelor's degree in political science and English, she appeared in 1990s Broadway productions of Some Americans Abroad and The Rose Tattoo. She made her cinematic debut in the 1992 feature Waterland.
She was cast as Betty Pike in the 2014 thriller A Good Marriage.
A native of The Bronx, she later settled in Greenwich Village with her entrepreneur husband, Peter Thum.
She wrote, produced, and directed a 1997 short film, Baggage, that featured actor Liev Schreiber.