At the age of six she composed her first song. She created her YouTube channel in December 2013.
In late 2017, she posted the music video to her song "Enemiga" featuring Colombian musician Mike Bahía to her YouTube channel. She's amassed more than 1 million followers on her Instagram account karenmendezkm.
She was born in Argentina, but went on to live in Canarias, Spain for several years. Her real name is Karen Romina Méndez Moltoni.
In October 2016, she released a music video singing alongside Sebastián Yatra for his hit single "Traicionera."