Lead guitarist for heavy metal band Metallica, the group known for albums like Kill 'Em All. He was also a member of Exodus, a thrash metal outfit.
He worked at Burger King to make enough money to buy a Marshall amplifier. He formed his first band in 1980.
As a heavy metal guitarist, he was ranked #11 on Rolling Stone's All-Time Best Guitarists list.
He married Rebecca Enrica Kestelyn on December 3, 1987. After their divorce in 1991, he married Lani Gruttadauro on January 31, 1998. He has two sons named Vincenzo and Angel.