The daughter of French filmmaker Francois Cluzet who won the country's Cesar award five times.
She was a shy child and the shyness was made worse by the unexpected death of her young sister.
She won her second Best Actress Cesar Award for her role in the 1999 film Comme Elle Respire.
Her boyfriend Bertrand Cantat was a lead singer with the French rock band Noir Désir and was convicted of murder after her death.
Melanie Laurent is another Cesar Award-winning actress.