Initially making a name for himself as a voice actor in the Shrek film franchise, Miles would earn his biggest role to date as Tim in Dreamworks' The Boss Baby. He voiced an ogre baby and "villager kid" for the movie Shrek Forever After.
His voice was first heard in the 2007 TV short Shrek the Halls.
He continued to voice ogre baby in the TV show Scared Shrekless and soon after could be heard as Gonzalo and Sir Timoteo in the video short Puss in Boots: The Three Diablos.
He is the grandson of animated and live-action film director Ralph Bakshi. His mother Gina Shay worked as a producer. He has a younger sister named Nina.
His voice and the voice of Alec Baldwin can both be heard in The Boss Baby.