In 1962, became the first Asian architect to be named an Honorary Fellow of the American Institute of Architects. His works included the Air Vietnam Headquarters, the campus of Huế University, and Đà Lạt's Atomic Research Center.
He studied at the Ecole des Beaux-Arts in Paris. He was awarded the First Grand Prize of Rome in 1955 and was an urban-planning researcher at the Villa Medicis from 1955 until 1958.
He designed the Independence Palace or Reunification Palace in Ho Chi Minh City.
He married Võ Thị Cơ, with whom he fathered eight children, among them Dr. Ngô Viết Nam Sơn, who followed in his father's footsteps to become an architect and planner.
He was born in the same country as astronaut Pham Tuan.