The oldest daughter of actor Charlie Sheen and Denise Richards, she was born in Los Angeles, California. She is an extremely popular content creator on TikTok, where she's earned over 70,000 fans on her samisheen account by primarily posting lip-sync videos.
Her parents met while filming the 2000 movie Good Advice and became romantically involved a year later on the set of Spin City. They married in the summer of 2002 and divorced when Sam was two years old.
Her mother starred in the E! reality series Denise Richards: It's Complicated.
She has a younger sister named Lola Rose Sheen, an adopted sister named Eloise Joni Richards, a half-sister named Cassandra Jade Estevez, and twin half-brothers named Bob and Max Sheen.
In 2011, her father, who was then starring on the CBS series Two and a Half Men, was replaced by Ashton Kutcher.