Starred as Charlie Harper on Two and a Half Men from 2003 to 2011, becoming TV's highest-paid actor in the process. After being fired from the show, he starred on FX's Anger Management from 2012 to 2014.
He had an uncredited cameo in the 2010 sequel to Wall Street. Born Carlos Estévez, he adopted the stage name of "Sheen" from his father, Martin Sheen.
He was married and had two kids with Denise Richards, but the couple divorced in 2006. He later married and had twins with Brooke Mueller, but the couple divorced in 2011. His brother Emilio also became an actor.