Decorated Paralympic wheelchair racer who became the youngest member, at 15 years of age, of the United States track & field national team in 2004.
She was born with spina bifida - a hole in her spine - and grew up using her arms to get around, without the aid of a wheelchair.
When her high school refused to let her participate in sports alongside able-bodied peers, she sued and won her landmark case.
She was adopted from a Russian orphanage by Deborah McFadden, who brought her to the U.S. and encouraged her sports activities.
David Weir is another successful Paralympian, who helped pave the way for McFadden.