Famous for her award-winning performance as Carla Bernaschi in the 2014 film Human Capital and for her roles as both director and actor in the acclaimed 2013 movie A Castle in Italy, she is also notable for her work in the 2003 film It's Easier for a Camel and in the 1998 movie Notes of Love.
She made her cinematic debut in the 1985 film Hotel de France.
She won a Cesar Award and was nominated for a Nastro d'Argento honor for her performance as Martine in the 1993 film Les Gens Normaux n'ont Rien d'Exceptionnel.
Born to a family of French and Italian descent, she is the sister of singer and fashion model Carla Bruni and the sister-in-law of French president Nicolas Sarkozy. During her five-year relationship with actor and filmmaker Louis Garrel, she adopted a Senegalese-born daughter.
She and Gaspard Ulliel appear together in the 2014 French film Saint Laurent.