The wife of former Indonesian President Susilo Bambang Yudhoyono, she served as the First Lady of Indonesia from 2004 to 2014.
She was briefly a medical student at Christian University of Indonesia. She would eventually earn a bachelor's in political science at Terbuka University in 1994.
In 2007, a rare butterfly species was named after her, Delias kristianiae.
Her father, Sarwo Edhie Wibowo, was a renowned military leader. She and her husband have two children, Agus Harimurti and Edhie Baskoro.
As the First Lady of Indonesia, she often worked alongside then-Vice President Jusuf Kalla.