Known for playing supporting characters in such films as Garden State, Philadelphia, and The Manchurian Candidate. She has also starred in HBO's The Leftovers and Hulu's The Handmaid's Tale. She has also performed in Broadway productions of The Seagull, Taking Sides, and Candida.
After taking premed classes at the College of the Holy Cross, she earned a Master of Fine Arts degree in acting from Depaul University's Goodman School of Drama and subsequently began her career as a Chicago-based stage actress.
She earned an Independent Spirit Award nomination for her role in the 2012 film Compliance and a Primetime Emmy Award nomination for her role in The Leftovers.
She and her six siblings grew up in Holyoke, Massachusetts. Her marriage to acting coach Larry Arancio resulted in children named Emily, Trust, and Liam.