Older fraternal twin of Jenna Bush and daughter of former U.S. President George W. Bush and former First Lady Laura Bush. She founded Global Health Corps in 2009.
She graduated from Yale University in May 2004.
She worked with AIDS patients in Botswana, South Africa and Tanzania.
She was named after her grandmother Barbara Bush, the wife of former U.S. President George H. W. Bush. In 2015 she was romantically linked to Franck Raharinosy.
She and Meghan McCain, daughter of Republican Senator John McCain, both publicly endorsed gay marriage in 2011.