Actor best known for his role as Dr. Chris Turk on the NBC series Scrubs. He also had a supporting role in the film Clueless, later reprising his role for the TV series of the same name. His other films include Remember the Titans and Kick-Ass 2. In 2016, he began hosting the game show Winsanity.
He first appeared on a Folgers Coffee commercial at age 17.
He played the jock Murray in the 1995 comedy film Clueless.
He was married to Lisa Askey from 2001 to 2005, and the couple had four children together. He then married CaCee Cobb in 2012. The couple welcomed a son named Rocco in 2013 and a daughter named Wilder in 2015.
He and Zach Braff played best friends Turk and J.D. in Scrubs.