Rose to fame on ABC's hit series Desperate Housewives and later had roles on the series Telenovela and Mother Up! In 2018, she was cast as the titular character's mom in the film Dora the Explorer. She has won multiple Screen Actors Guild Awards and was named Philanthropist of the Year in 2009 by THR.
From 2002 until 2004 she was married to Tyler Christopher. She married Tony Parker in 2007, and the couple divorced in 2010. She married Jose Antonio Baston in 2016 and she welcomed her first child, Santiago, in 2018.