Known for being the first female CEO and Chairperson of IBM, she had previously worked as both a systems engineer and a consultant for the computer company. In the latter capacity, she fought for IBM's purchase of the PricewaterhouseCoopers Consulting Company.
After graduating from Northwestern University with degrees in electrical engineering and computer science, she worked briefly for the General Motors Institute (Kettering University) in Flint, Michigan.
She served on the board of the Memorial Sloan-Kettering Cancer Center.
Born and raised in Chicago, Illinois, she later married business investor Mark Anthony Rometty.
She and Louis Gerstner, Jr. both held the office of CEO of IBM.