He began playing basketball at an early age. He first gained widespread renown for his play at Chaminade College Preparatory School in St. Louis, Missouri.
He played in the 2014 and 2015 FIBA Under-17 and Under-19 World Championships, respectively, for the United States.
He was born to Brandy and Justin Tatum. He has a younger brother named Jaycob. He has a son named Jayson Jr.