An English theologian, priest, and writer, he is known for his Christian-themed works. Also a mystery writer, he published such detective novels as The Viaduct Murder and The Three Taps.
He became an Anglican priest in 1912 and was subsequently appointed Chaplain of Trinity College. Later, however, he converted to Roman Catholicism.
Working from both Greek and Hebrew sources, he successfully re-translated the Latin Vulgate Bible into English under the supervision of the Catholic clergy.
He grew up in England and attended Eton College and Balliol College, Oxford. His father, Edmund Knox, was the Bishop of Manchester.
Knox was ordained as a Roman Catholic priest in 1918. Fellow religious leader Jeff Probst was also ordained, but as a minister of the Universal Church of Life.