She was immortalized for starring on the series Buffy the Vampire Slayer, for which she won five Teen Choice Awards. She also starred in Cruel Intentions, winning an MTV Award for Best Kiss with Selma Blair.
She was scouted by an agent at age four, which led to her appearance in commercials and television films.
She won an Emmy Award in 1995 for her role as Kendall Hart on the soap opera All My Children. She voiced April O'Neil in 2007's TMNT.
She married Freddie Prinze Jr. in 2002, and the couple had a daughter named Charlotte and a son named Rocky James.
She and Alyson Hannigan both starred on Buffy the Vampire Slayer.