He started acting when he was 8, with his first credit coming in the 1973 film Yaadon Ki Baaraat, directed by his uncle, Nasir Hussain.
In 2001, he founded his own production company, Aamir Khan Productions.
He was married to Reena Dutta from 1986 to 2002, then in 2005, he married Kiran Rao. He has two sons, Azad and Junaid, and a daughter, Ira.
His 2001 film Lagaan, starring Rachel Shelley, was nominated for an Academy Award for Best Foreign Film.