He attended the Ringling Brothers and Barnum & Bailey Clown College in his youth.
He won the 2005 Tony Award for Best Actor in a Play for his role as George in Who's Afraid of Virginia Woolf?
His parents are Elizabeth and Horace G. Irwin, a teacher and aerospace engineer. He married Martha Roth in 1990 and he has a son named Santos.
He played Anne Hathaway's on-screen father in Rachel Getting Married.