Painter associated with the Mexican Mural Movement. He became well known for his frescoes, paintings, and monumental political murals. He painted murals in Mexico City, Chapingo, Cuernavaca, San Francisco, Detroit, and New York City from 1922 until 1953.
He came under the influence of such cubism painters as Pablo Picasso and Georges Braque, practicing the style from 1913 until 1917. He then embraced post-impressionism after coming under the influence of Paul Cezanne in 1917.
His famous mural, History of Mexico, depicted 17 revolutionary figures and was painted on a wall in the courtyard of Mexico City's Palacio Nacional.
His twin brother, Carlos, died at age two. He was married four times: to Angelina Beloff, Guadalupe Marin, painter Frida Kahlo, and Emma Hurtado. He had three daughters named Ruth, Marika, and Guadalupe, as well as one son named Diego.
His circle of friends included Italian painter Amedeo Modigliani, who painted a portrait of Rivera in 1914.