Emmy-nominated actress who played the frazzled mom, Lois Wilkerson, on the television series Malcolm in the Middle She later played Pam on the series Us & Them.
She spent time studying and participating in theater groups at Yale University.
She founded the nonprofit organization Clothes Off Our Back, which auctioned celebrity clothing for children's charities.
She married Bradley Whitford in 1992, and the couple welcomed their first child in 1997.
Bryan Cranston played her husband on Malcolm in the Middle.