Before deciding to become an actor, he wanted to pursue a career in the field of sports medicine.
He won a Favorite Actor TV Guide Award in 2011 for his role in Supernatural.
He has an older brother named Joshua and a younger sister named Mackenzie. He married Danneel Harris in 2010 and the couple welcomed a daughter named Justice Jay on May 30, 2013. He and Danneel then gave birth to a pair of twins, Zeppelin and Arrow, in December 2016.
He appeared in the Dark Angel TV series in 2001 with Jessica Alba.