Most followed on the network musical.ly, with more than 3.3 million followers on his justindrewblake account, he is also popular on Instagram, with more 1.1 million followers.
He came out as transgender in 2015.
He has a self-titled YouNow channel with more than 190,000 fans.
He created a YouTube channel called Blake Boys with his brother Danny and his good friend Damon. He has an older brother named Jacob. He was in a relationship with Raegan Beast from 2016 to 2017. He was often seen with fellow muser Tyler Brown, whom he later confirmed he was dating in October 2017.
He is good friends with fellow muser Jordan Brooke and has made appearances on her social media.