Known for her work with film director and fellow producer Judd Apatow, she produced such box office hits as The 40-Year-Old Virgin, Anchorman: The Legend of Ron Burgundy, Forgetting Sarah Marshall, and Elf.
She grew up on an Ontario farm and left high school to relocate to Los Angeles, California, where she worked with such directors as Mike Binder and Hart Bochner.
Early in her career, she co-produced the popular film Meet the Parents.
She and her famous husband, film actor Edward Norton, welcomed their first child in early 2013.
She was one of the producers of Pineapple Express, a 2008 comedy film written by and starring Seth Rogen.