American author of detective fiction who was best known for her Alphabet series, which focuses on the adventures of private investigator Kinsey Millhone. Popular titles in the series include "A" is for Alibi, "K" is for Killer, and "V" is for Vengeance.
After graduating from the University of Louisville, she worked as a cashier and a secretary.
She received the Grand Master Award from the Mystery Writers of America association.
She and her third husband, Steven F. Humphrey, lived in both California and Kentucky. Her first two marriages produced three children.
In an episode of The Sopranos, Edie Falco's character can be seen reading Grafton's novel "G" is for Gumshoe.