Starred as Cindy Campbell in the Scary Movie film franchise. She also played Zoey in The Dictator and co-produced and starred in the 2008 film The House Bunny. She plays the lead character Christy on the CBS series Mom.
She appeared in a frozen-yogurt commercial while in high school.
She played Erica in the last season of the TV series Friends. She began hosting the podcast Anna Faris is Unqualified.