Her parents married while Reese was six months pregnant with her in Charleston. Her parents divorced in 2007 after separating in 2006.
She has accrued a following of more than 1 million on Instagram.
She has a younger brother named Deacon Reese Phillippe and a half brother named Tennessee from her mother's second marriage to Jim Toth. Her half sister Kai is from her father's relationship with Alexis Knapp.
She was named after actress Ava Gardner.