Academy Award-winning actress best known for her role in the 1980 film Melvin and Howard. She has also appeared in the films What's Eating Gilbert Grape and Back to the Future Part III.
She was discovered by Jack Nicholson, who cast her in the 1978 picture Goin' South.
She appeared in such early 21st-century films as Four Christmases, Step Brothers, and The Proposal.
She had a son named Charlie and a daughter named Lilly with actor Malcolm McDowell, whom she was married to from 1980 to 1990. She then married Ted Danson in 1995.
She had a memorable role in Elf, playing the wife of James Caan's character.