Best known for playing Juliet in Franco Zeffirelli's 1968 film, Romeo and Juliet. She later starred in several horror films including Virus and Death on The Nile.
She studied at the Italia Conti Academy drama school in London.
Hussey has identified as suffering from agoraphobia.
She was married to Dean Paul Martin in 1971, and the couple had a son named Alexander in 1973. She has another son named Maximillian and a daughter named India from later relationships.
She worked with Ben Savage in Boy Meets World.