He began his acting career in advertisements for soft drinks and fast food on Puerto Rican television.
He has released over five #1 hit Billboard albums and sold over 70 million albums, which include Almas del Silencio in 2003 and Life in 2005. In 2012, he guest-starred as a Spanish teacher on the TV series Glee, where he performed songs by Madonna and LMFAO.
In 2017, he married Jwan Yosef. He was previously in a relationship with economist Carlos Gonzalez from 2011 to 2014. He had fraternal twins named Matteo and Valentino in 2008. In early 2019, he welcomed a daughter named Lucía and in October of that same year, he had another son named Renn. In 2023, he and Yosef announced that they were getting a divorce.