He married actress Scarlett Johansson in September 2008, and the couple divorced in July 2011. He then married Blake Lively in South Carolina on September 9, 2012 and the couple had their first child, a daughter named James, in December of 2014 followed by their second daughter Inez in September 2016. They welcomed a third daughter named Betty in October 2019. In September 2022, Ryan and Blake announced that they were expecting their fourth child together. That child was born in February of 2023.