Stars as the loud-mouthed Erlich Bachman on the HBO series Silicon Valley. He has also appeared in such films as Cloverfield, Transformers: Age of Extinction, and Deadpool. In 2014, he voiced the character Fred in the Disney film Big Hero 6.
He was a member of the comedy group Recess during his college years at George Washington University.
He played the role of Helpful Stainer, who gave advice to his friend with girl issues, in the film She's Out of My League. He underwent brain surgery in 2010 to fix an abnormal connection in his frontal lobe.
His sister Morgan is also a comedian. He got engaged to Kate Gorney in 2014 and they married in September of 2015.