Nicknamed "Z-Bo," he won the NBA's Most Improved Player award with the Portland Trail Blazers in 2004. He was selected to his first NBA All-Star team as a member of the Memphis Grizzlies in 2010. After spending eight seasons in Memphis, he signed with the Sacramento Kings in 2017.
In 2011, he helped lead the 8-seeded Grizzlies to an improbable 6-game upset of the top-seeded San Antonio Spurs.
In 2014, he married Faune Drake. He has five children: Zacharia, Zaqary, Zachary Randolph Jr., MaZiya, and MacKenley.
He and Marc Gasol combined to give the Grizzlies one of the most physical and imposing front courts in the NBA.