He made his entertainment debut at age 16 on the series Gimik 2010.
His debut self-titled solo album, which was released in 2012, was certified double platinum.
Born in the Philippines, he is the son of actors Rommel Padilla and Karla Estrada. He has a sister named Carmella and half-siblings from both his mother and his father's other relationships. One of his half-brothers is JC Padilla. He has been in a relationship with Kathryn Bernardo. They broke up in November 2023.