Daughter of celebrated comedy director/producer Judd Apatow and actress Leslie Mann. She is a child actress and writer best known for her roles in the movies Knocked Up, Funny People, and This Is 40. She also had a recurring role on the HBO series Girls and began starring in HBO's Euphoria in 2019.
She made her film debut in Knocked Up in 2007. She reprised this role in the 2012 spin-off film This is 40.
In 2013 Time magazine voted her as having one of the best Twitter feeds. She also contributes as a writer to Hello Giggles, a website founded by actress Zooey Deschanel.
In addition to working with her famous parents, she also has acted alongside her little sister Iris Apatow.
She plays the daughter of Paul Rudd's character in both Knocked Up and This is 40.